UFC Fight Night 145: Błachowicz vs. Santos was held on Feb 23, 2019 at the O2 arena in Prague, Czech Republic.
| Weight Class | Fight Card | Winner |
| Light Heavyweight | Jan Błachowicz vs. Thiago Santos | Thiago Santos |
| Heavyweight | Stefan Struve vs. Marcos Rogério de Lima | Stefan Struve |
| Light Heavyweight | Gian Villante vs. Michal Oleksiejczuk | Michal Oleksiejczuk |
| Women's Flyweight | Liz Carmouche vs. Lucie Pudilová | Liz Carmouche |
| Bantamweight | John Dodson vs. Petr Yan | Petr Yan |
| Light Heavyweight | Magomed Ankalaev vs. Klidson Abreu | Magomed Ankalaev |
| Weight Class | Fight Card | Winner |
| Welterweight | Carlo Pedersoli Jr. vs. Dwight Grant | Dwight Grant |
| Featherweight | Daniel Teymur vs. Chris Fishgold | Chris Fishgold |
| Women's Flyweight | Veronica Macedo vs. Gillian Robertson | Gillian Robertson |
| Lightweight | Damir Hadžović vs. Polo Reyes | Damir Hadžović |
| Welterweight | Michel Prazeres vs. Ismail Naurdiev | Ismail Naurdiev |
| Lightweight | Rustam Khabilov vs. Carlos Diego Ferreira | Carlos Diego Ferreira |
| Lightweight | Damir Ismagulov vs. Joel Alvarez | Damir Ismagulov |
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