Offensive Positions
| POSITION | STARTER | SECOND | THIRD+ |
| Quarterback | Jacoby Brissett | Joshua Dobbs | Kellen Mond Deshaun Watson |
| Running Back | Nick Chubb | Kareem Hunt | D'Ernest Johnson Demetric Felton Jerome Ford |
| Wide Receiver | Amari Cooper | Donovan Peoples-Jones | David Bell Michael Woods II Demetric Felton Anthony Schwartz Jakeem Grant Isaiah Weston |
| Tight End | David Njoku | Harrison Bryant | Pharaoh Brown Jesse James |
| Left Tackle | Jedrick Wills | James Hudson | — |
| Left Guard | Joel Bitonio | Drew Forbes | — |
| Center | Ethan Pocic | Michael Dunn | — |
| Right Guard | Wyatt Teller | Hjalte Froholdt | — |
| Right Tackle | Jack Conklin | Chris Hubbard | — |
Defensive Positions
| POSITION | STARTER | SECOND | THIRD+ |
| Left Defensive End | Myles Garrett | Isaiah Thomas | Isaac Rochell Chase Winovich |
| Right Defensive End | Jadeveon Clowney | Alex Wright | Stephen Weatherly Chris Odom |
| Left Defensive Tackle | Jordan Elliott | Tommy Togiai | — |
| Right Defensive Tackle | Taven Bryan | Perrion Winfrey | — |
| Strongside Linebacker | Sione Takitaki | Jordan Kunaszyk | — |
| Middle Linebacker | Deion Jones | Jacob Phillips | Anthony Walker |
| Weakside Linebacker | Jeremiah Owusu-Koramoah | Tony Fields II | — |
| Right Cornerback | Greg Newsome II | Martin Emerson | Herb Miller Thomas Graham Jr. |
| Left Cornerback | Denzel Ward | Greedy Williams | A.J. Green |
| Strong Safety | Grant Delpit | Ronnie Harrison | — |
| Free Safety | John Johnson | D'Anthony Bell | — |
Special Teams Positions
| POSITION | STARTER | SECOND | THIRD+ |
| Punter | Corey Bojorquez | — | — |
| Kicker | Cade York | — | — |
| Long Snapper | Charley Hughlett | — | — |
| Holder | Corey Bojorquez | — | — |
| Punt Returner | Demetric Felton | Donovan Peoples-Jones | Jakeem Grant |
| Kick Returner | D'Ernest Johnson | David Bell | Jerome Ford Jakeem Grant |
