| Date | Match | Time (ET) |
| October 11, 2018 | Philadelphia Eagles vs New York Giants | 8:20 PM |
| October 14, 2018 | Tampa Bay Buccaneers vs Atlanta Falcons | 1:00 PM |
| October 14, 2018 | Pittsburgh Steelers vs Cincinnati Bengals | 1:00 PM |
| October 14, 2018 | Los Angeles Chargers vs Cleveland Browns | 1:00 PM |
| October 14, 2018 | Buffalo Bills vs Houston Texans | 1:00 PM |
| October 14, 2018 | Chicago Bears vs Miami Dolphins | 1:00 PM |
| October 14, 2018 | Arizona Cardinals vs Minnesota Vikings | 1:00 PM |
| October 14, 2018 | Indianapolis Colts vs New York Jets | 1:00 PM |
| October 14, 2018 | Seattle Seahawks vs Oakland Raiders | 1:00 PM |
| October 14, 2018 | Carolina Panthers vs Washington Redskins | 1:00 PM |
| October 14, 2018 | Los Angeles Rams vs Denver Broncos | 4:05 PM |
| October 14, 2018 | Jacksonville Jaguars vs Dallas Cowboys | 4:25 PM |
| October 14, 2018 | Baltimore Ravens vs Tennessee Titans | 4:25 PM |
| October 14, 2018 | Kansas City Chiefs vs New England Patriots | 8:20 PM |
| October 15, 2018 | San Francisco 49ers vs Green Bay Packers | 8:15 PM |
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