| Date | Match | Time (ET) |
| December 13, 2018 | Los Angeles Chargers vs Kansas City Chiefs | 8:20 PM |
| December 15, 2018 | Cleveland Browns vs Denver Broncos | 4:30 PM |
| December 15, 2018 | Houston Texans vs New York Jets | 4:30 PM |
| December 16, 2018 | Arizona Cardinals vs Atlanta Falcons | 1:00 PM |
| December 16, 2018 | Tampa Bay Buccaneers vs Baltimore Ravens | 1:00 PM |
| December 16, 2018 | Detroit Lions vs Buffalo Bills | 1:00 PM |
| December 16, 2018 | Green Bay Packers vs Chicago Bears | 1:00 PM |
| December 16, 2018 | Oakland Raiders vs Cincinnati Bengals | 1:00 PM |
| December 16, 2018 | Dallas Cowboys vs Indianapolis Colts | 1:00 PM |
| December 16, 2018 | Washington Redskins vs Jacksonville Jaguars | 1:00 PM |
| December 16, 2018 | Miami Dolphins vs Minnesota Vikings | 1:00 PM |
| December 16, 2018 | Tennessee Titans vs New York Giants | 1:00 PM |
| December 16, 2018 | Seattle Seahawks vs San Francisco 49ers | 4:05 PM |
| December 16, 2018 | New England Patriots vs Pittsburgh Steelers | 4:25 PM |
| December 16, 2018 | Philadelphia Eagles vs Los Angeles Rams | 8:20 PM |
| December 17, 2018 | New Orleans Saints vs Carolina Panthers | 8:15 PM |
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