| Date | Match | Time (ET) |
| September 27, 2018 | Minnesota Vikings vs Los Angeles Rams | 8:20 PM |
| September 30, 2018 | Cincinnati Bengals vs Atlanta Falcons | 1:00 PM |
| September 30, 2018 | Tampa Bay Buccaneers vs Chicago Bears | 1:00 PM |
| September 30, 2018 | Detroit Lions vs Dallas Cowboys | 1:00 PM |
| September 30, 2018 | Buffalo Bills vs Green Bay Packers | 1:00 PM |
| September 30, 2018 | Houston Texans vs Indianapolis Colts | 1:00 PM |
| September 30, 2018 | New York Jets vs Jacksonville Jaguars | 1:00 PM |
| September 30, 2018 | Miami Dolphins vs New England Patriots | 1:00 PM |
| September 30, 2018 | Philadelphia Eagles vs Tennessee Titans | 1:00 PM |
| September 30, 2018 | Seattle Seahawks vs Arizona Cardinals | 4:05 PM |
| September 30, 2018 | Cleveland Browns vs Oakland Raiders | 4:05 PM |
| September 30, 2018 | San Francisco 49ers vs Los Angeles Chargers | 4:25 PM |
| September 30, 2018 | New Orleans Saints vs New York Giants | 4:25 PM |
| September 30, 2018 | Baltimore Ravens vs Pittsburgh Steelers | 8:20 PM |
| October 1, 2018 | Kansas City Chiefs vs Denver Broncos | 8:15 PM |
